Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 11/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709571 | 0.81 | TBXAS1 (0.67) | TBXAS1 | |
| SCHEMBL10622938 | 0.79 | TBXAS1 (0.57) | TBXAS1CHRNA7ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9732456 | 0.78 | TBXAS1 (0.47) | TBXAS1CHRNA7ALDH1A1PTAFRTDP1 | |
| SCHEMBL5962751 | 0.78 | TBXAS1 (0.64) | TBXAS1CHRNA7ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL30178297 | 0.78 | TBXAS1 (0.64) | TBXAS1CHRNA7ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL7287637 | 0.77 | TDP1 (0.54) | TBXAS1TDP1L3MBTL1 | |
| SCHEMBL9709633 | 0.77 | TBXAS1 (0.50) | TBXAS1 | |
| SCHEMBL3957320 | 0.77 | CYP4F2 (0.55) | TBXAS1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9733092 | 0.76 | TBXAS1 (0.52) | TBXAS1CHRNA7PTAFR | |
| SCHEMBL9732015 | 0.76 | TBXAS1 (0.48) | TBXAS1CHRNA7ALDH1A1PTAFRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493324-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |