Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.48 |
| ▸ | CD38 | P28907 | 8/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709806 | 0.90 | AGTR1 (0.46) | AGTR1AGTR2CD38CYP3A4 | |
| SCHEMBL9709754 | 0.90 | AGTR1 (0.47) | AGTR1AGTR2CD38 | |
| SCHEMBL9709829 | 0.89 | AGTR1 (0.47) | AGTR1AGTR2CD38 | |
| SCHEMBL3051876 | 0.89 | CD38 (0.46) | AGTR1AGTR2CD38MEN1KMT2A | |
| SCHEMBL9709849 | 0.89 | CD38 (0.47) | AGTR1AGTR2CD38CYP3A4KCNH2 | |
| SCHEMBL3058746 | 0.87 | AGTR1 (0.50) | AGTR1AGTR2MEN1KMT2A | |
| SCHEMBL9710179 | 0.86 | AGTR1 (0.47) | AGTR1AGTR2CD38 | |
| SCHEMBL9704665 | 0.82 | AGTR1 (0.70) | AGTR1AGTR2 | |
| SCHEMBL9464440 | 0.81 | AGTR1 (0.70) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL9495708 | 0.81 | AGTR1 (0.68) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | claimed |
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |