Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | AGT | P01019 | 2/20 | 0.37 |
| ▸ | USP1 | O94782 | 2/20 | 0.35 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709718 | 0.91 | AGTR1 (0.42) | AGTR1AGTR2P2RX7AGTUSP1 | |
| SCHEMBL3061585 | 0.88 | AGTR1 (0.44) | AGTR1AGTR2AGTMEN1KMT2A | |
| SCHEMBL9709679 | 0.82 | CD38 (0.45) | AGTR1AGTR2AGTMEN1KMT2A | |
| SCHEMBL9592346 | 0.80 | AGTR1 (0.49) | AGTR1AGTR2AGT | |
| SCHEMBL9709873 | 0.79 | AGTR1 (0.45) | AGTR1AGTR2AGT | |
| SCHEMBL9709709 | 0.79 | AGTR1 (0.38) | AGTR1AGTR2P2RX7AGTTOP1 | |
| SCHEMBL9709866 | 0.78 | AGTR1 (0.47) | AGTR1AGTR2CDC7 | |
| SCHEMBL9709627 | 0.76 | AGTR1 (0.38) | AGTR1AGTR2AGT | |
| SCHEMBL9177563 | 0.76 | AGTR1 (0.47) | AGTR1AGTR2AGT | |
| SCHEMBL9093218 | 0.75 | AGTR1 (0.48) | AGTR1AGTR2P2RX7AGTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |