Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 8/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 8/20 | 0.45 |
| ▸ | AGT | P01019 | 2/20 | 0.42 |
| ▸ | ACP1 | P24666 | 4/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3061585 | 0.90 | AGTR1 (0.44) | AGTR1AGTR2AGTACP1NCF1 | |
| SCHEMBL9709718 | 0.89 | AGTR1 (0.42) | AGTR1AGTR2AGTPDE4APDE4B | |
| SCHEMBL9709729 | 0.89 | AGTR1 (0.44) | AGTR1AGTR2AGT | |
| SCHEMBL9709679 | 0.82 | CD38 (0.45) | AGTR1AGTR2AGT | |
| SCHEMBL9709702 | 0.79 | AGTR1 (0.42) | AGTR1AGTR2AGT | |
| SCHEMBL13146764 | 0.78 | AGTR1 (0.55) | AGTR1AGTR2AGT | |
| SCHEMBL9178505 | 0.77 | AGTR1 (0.47) | AGTR1AGTR2AGT | |
| SCHEMBL9709757 | 0.77 | AGTR1 (0.52) | AGTR1AGTR2ACP1PDE4APDE4B | |
| SCHEMBL9590931 | 0.76 | AGTR1 (0.61) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| SCHEMBL9093218 | 0.76 | AGTR1 (0.48) | AGTR1AGTR2AGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |