Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | HPGDS | O60760 | 1/20 | 0.52 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709882 | 1.00 | DAO (0.59) | DAOCES2CES1HPGDSERCC5 | |
| SCHEMBL9710031 | 0.82 | CES2 (0.54) | DAOCES2CES1HPGDSRAB9A | |
| SCHEMBL9710026 | 0.82 | CES2 (0.54) | DAOCES2CES1HPGDSRAB9A | |
| SCHEMBL28911298 | 0.82 | DAO (0.57) | DAOCES2CES1HPGDSERCC5 | |
| SCHEMBL10914699 | 0.82 | DAO (0.57) | DAOCES2CES1HPGDSERCC5 | |
| SCHEMBL10914702 | 0.82 | DAO (0.57) | DAOCES2CES1HPGDSERCC5 | |
| SCHEMBL28465227 | 0.82 | CES2 (0.54) | DAOCES2CES1HPGDSRAB9A | |
| SCHEMBL8635237 | 0.81 | DAO (0.52) | DAOCES2CES1HPGDSERCC5 | |
| SCHEMBL9115701 | 0.81 | DAO (0.52) | DAOCES2CES1HPGDSERCC5 | |
| SCHEMBL9117060 | 0.79 | DAO (0.53) | DAOCES2CES1HPGDSERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020689-A1 | ANTIBACTERIAL PENEM DERIVATIVES | SMITHKLINE BEECHAM P.L.C. (GB) | 1992-11-26 | — | — | WO | disclosed |