Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648541 | 0.84 | TSHR (0.48) | DAOCES2CES1TSHRKMT2A | |
| SCHEMBL9709882 | 0.81 | DAO (0.59) | DAOCES2CES1ERCC5FEN1 | |
| SCHEMBL9709878 | 0.81 | DAO (0.59) | DAOCES2CES1ERCC5FEN1 | |
| SCHEMBL2924389 | 0.77 | RAB9A (0.45) | DAOCES2CES1HPGDSTSHR | |
| SCHEMBL10914699 | 0.76 | DAO (0.57) | DAOCES2CES1ERCC5FEN1 | |
| SCHEMBL28911298 | 0.76 | DAO (0.57) | DAOCES2CES1ERCC5FEN1 | |
| SCHEMBL10914702 | 0.76 | DAO (0.57) | DAOCES2CES1ERCC5FEN1 | |
| SCHEMBL9115701 | 0.75 | DAO (0.52) | DAOCES2CES1ERCC5FEN1 | |
| SCHEMBL9857912 | 0.74 | HPGDS (0.49) | DAOCES2CES1HPGDSTSHR | |
| SCHEMBL11463757 | 0.74 | DAO (0.50) | DAOCES2CES1ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0694029-B1 | NOVEL METHOD FOR PREPARING BETA-ALKOXY ACRYLIC ACID | ROUSSEL UCLAF (FR) | 1998-07-29 | — | — | EP | disclosed |
| EP-0694029-A1 | NOVEL METHOD FOR PREPARING BETA-ALKOXY ACRYLIC ACID | ROUSSEL UCLAF (FR) | 1996-01-31 | — | — | EP | disclosed |
| WO-1994024085-A1 | NOVEL METHOD FOR PREPARING β-ALKOXY ACRYLIC ACID | ROUSSEL UCLAF (FR) | 1994-10-27 | — | — | WO | disclosed |