Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 9/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709790 | 0.87 | AGTR1 (0.47) | AGTR1AGTR2MEN1KMT2AGPR35 | |
| SCHEMBL9709643 | 0.85 | AGTR1 (0.47) | AGTR1AGTR2MEN1KMT2AGPR35 | |
| SCHEMBL9709759 | 0.85 | AGTR1 (0.45) | AGTR1AGTR2MEN1KMT2AGPR35 | |
| SCHEMBL9709866 | 0.84 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9709886 | 0.83 | AGTR1 (0.46) | AGTR1AGTR2MEN1KMT2A | |
| SCHEMBL9709809 | 0.83 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL3058746 | 0.81 | AGTR1 (0.50) | AGTR1AGTR2MEN1KMT2A | |
| SCHEMBL9709854 | 0.80 | MEN1 (0.63) | AGTR1AGTR2MEN1KMT2AGPR35 | |
| SCHEMBL9709692 | 0.79 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9704665 | 0.78 | AGTR1 (0.70) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |