Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.59 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | ACP1 | P24666 | 4/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.45 |
| ▸ | NQO2 | P16083 | 3/20 | 0.45 |
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3058746 | 0.88 | AGTR1 (0.50) | MEN1KMT2AACP1AGTR1AGTR2 | |
| SCHEMBL9709759 | 0.86 | AGTR1 (0.45) | MEN1KMT2AGPR35ACP1AGTR1 | |
| SCHEMBL9709600 | 0.85 | AGTR1 (0.48) | MEN1KMT2AGPR35AGTR1AGTR2 | |
| SCHEMBL9709643 | 0.84 | AGTR1 (0.47) | MEN1KMT2AGPR35AGTR1AGTR2 | |
| SCHEMBL9710208 | 0.83 | AGTR1 (0.47) | MEN1KMT2AGPR35AGTR1AGTR2 | |
| SCHEMBL3051876 | 0.82 | CD38 (0.46) | MEN1KMT2AGPR35ACP1AGTR1 | |
| SCHEMBL9709904 | 0.82 | AGTR1 (0.46) | MEN1KMT2AACP1AGTR1AGTR2 | |
| SCHEMBL9709790 | 0.81 | AGTR1 (0.47) | MEN1KMT2AGPR35AGTR1AGTR2 | |
| SCHEMBL9709642 | 0.80 | AGTR1 (0.48) | MEN1KMT2AAGTR1AGTR2 | |
| SCHEMBL9709928 | 0.80 | AGTR1 (0.44) | MEN1KMT2AGPR35AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | claimed |
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |