Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710008 | 0.91 | CYP19A1 (0.41) | EPHX2CYP19A1LMNAHTT | |
| SCHEMBL9709892 | 0.85 | KDM1A (0.40) | EPHX2KCNH2LMNAHPGD | |
| Arpromidine SCHEMBL9710060 | 0.85 | NPY1R (0.41) | — | |
| SCHEMBL7285709 | 0.84 | NPY1R (0.41) | EPHX2 | |
| SCHEMBL7300955 | 0.84 | NPY1R (0.49) | — | |
| SCHEMBL7298207 | 0.82 | EPHX2 (0.44) | EPHX2CYP2C9CYP2C19SLC1A3SLC1A2 | |
| SCHEMBL9828096 | 0.81 | NPY1R (0.38) | — | |
| SCHEMBL9828126 | 0.81 | EPHX2 (0.39) | EPHX2KCNH2 | |
| SCHEMBL7285697 | 0.81 | CYP19A1 (0.38) | EPHX2CYP19A1LMNAHTTNPSR1 | |
| SCHEMBL7280178 | 0.80 | EPHX2 (0.42) | EPHX2CYP2C9CYP2C19SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022295-A1 | USE OF GUANIDINE DERIVATIVES IN THE PREPARATION OF A DRUG FOR THE TREATMENT OF SEPSIS AND SEPSIS-LIKE CONDITIONS AND SEPTIC SHOCK | NEUGEBAUER EDMUND (DE) | 1992-12-23 | — | — | WO | disclosed |