Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arpromidine SCHEMBL9710060 | 0.96 | NPY1R (0.41) | NPY1RMEN1KMT2A | |
| SCHEMBL9827438 | 0.93 | ALDH1A1 (0.40) | — | |
| SCHEMBL9827663 | 0.89 | ALDH1A1 (0.40) | — | |
| SCHEMBL9710008 | 0.87 | CYP19A1 (0.41) | MEN1KMT2A | |
| SCHEMBL9828176 | 0.86 | HRH1 (0.45) | — | |
| SCHEMBL9827825 | 0.86 | CHRM2 (0.45) | — | |
| SCHEMBL9828102 | 0.84 | NPY1R (0.55) | NPY1R | |
| SCHEMBL9828126 | 0.84 | EPHX2 (0.39) | — | |
| SCHEMBL7312755 | 0.84 | CNR1 (0.40) | — | |
| SCHEMBL7277082 | 0.81 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302896-B1 | N-(W-SUBSTITUTED ALKYL)-N'-[(IMIDAZOLE-4-YL)ALKYL]GUANIDINE | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-08-14 | — | — | EP | claimed |
| EP-0302896-B1 | N-(W-SUBSTITUTED ALKYL)-N'-[(IMIDAZOLE-4-YL)ALKYL]GUANIDINE | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |
| US-5021431-A | H-1 antagonist, h-2 agonist for treating hypertension, cardiac disease or arterial occlusion | HEUMANN PHARMA GMBH & CO. (DE) | 1991-06-04 | — | — | US | disclosed |
| EP-0199845-B1 | IMIDAZOLYLALKYLGUANIDIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HEUMANN PHARMA GMBH & CO (DE) | 1990-08-01 | — | — | EP | disclosed |
| EP-0199845-A1 | Imidazolylalkylguanidin derivatives, process for their preparation and pharmaceutical compositions containing them | HEUMANN PHARMA GMBH & CO (DE) | 1986-11-05 | — | — | EP | disclosed |