Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285523 | 0.92 | CYP19A1 (0.40) | CYP19A1LMNANPSR1 | |
| SCHEMBL7285906 | 0.91 | CYP19A1 (0.39) | CYP19A1TBXAS1CASR | |
| SCHEMBL7285350 | 0.91 | CYP19A1 (0.37) | CYP19A1 | |
| SCHEMBL7295465 | 0.90 | CYP19A1 (0.36) | CYP19A1 | |
| SCHEMBL7433406 | 0.85 | PTGDR2 (0.37) | LMNACASR | |
| SCHEMBL7279920 | 0.85 | CHRM2 (0.41) | LMNANPSR1 | |
| Hydrochloric Acid SCHEMBL7428983 | 0.84 | PTGDR2 (0.36) | LMNA | |
| SCHEMBL7286799 | 0.82 | SIGMAR1 (0.38) | LMNANPSR1 | |
| SCHEMBL9709997 | 0.81 | EPHX2 (0.48) | CYP19A1EPHX2LMNAHTTNPSR1 | |
| SCHEMBL7285767 | 0.79 | PTGDR2 (0.34) | EPHX2LMNAHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262448-B1 | IMIDAZOLYLGUANIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | HEUMANN PHARMA GMBH & CO (DE) | 1991-12-18 | — | — | EP | claimed |
| EP-0262448-B1 | IMIDAZOLYLGUANIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | HEUMANN PHARMA GMBH & CO (DE) | 1991-12-18 | — | — | EP | disclosed |