Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710082 | 1.00 | TBXAS1 (0.62) | TBXAS1TBXA2R | |
| SCHEMBL9732269 | 0.89 | TBXAS1 (0.60) | TBXAS1TBXA2R | |
| SCHEMBL9732992 | 0.80 | TBXAS1 (0.85) | TBXAS1TBXA2R | |
| SCHEMBL9731854 | 0.80 | TBXAS1 (0.63) | TBXAS1 | |
| SCHEMBL9709545 | 0.79 | TBXAS1 (0.63) | TBXAS1TBXA2R | |
| SCHEMBL9709547 | 0.79 | TBXAS1 (0.63) | TBXAS1TBXA2R | |
| SCHEMBL1583762 | 0.79 | TBXAS1 (0.90) | TBXAS1 | |
| SCHEMBL30612524 | 0.79 | TBXAS1 (0.90) | TBXAS1 | |
| SCHEMBL1858925 | 0.78 | HDAC1 (0.58) | — | |
| SCHEMBL744045 | 0.77 | TBXAS1 (1.00) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153214-A | Treating cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0493324-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |