Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 12/20 | 0.63 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709545 | 1.00 | TBXAS1 (0.63) | TBXAS1FFAR4TBXA2RKMT2ACHRNB2 | |
| SCHEMBL9709655 | 0.85 | TBXAS1 (0.58) | TBXAS1FFAR4TBXA2R | |
| SCHEMBL9709646 | 0.85 | TBXAS1 (0.58) | TBXAS1FFAR4TBXA2R | |
| SCHEMBL9710086 | 0.79 | TBXAS1 (0.62) | TBXAS1TBXA2R | |
| SCHEMBL9710082 | 0.79 | TBXAS1 (0.62) | TBXAS1TBXA2R | |
| SCHEMBL9709493 | 0.78 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL9709541 | 0.78 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL9709498 | 0.78 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL15429528 | 0.77 | CHRNB2 (0.56) | TBXAS1FFAR4KMT2ACHRNB2CHRNA4 | |
| SCHEMBL30954573 | 0.77 | CHRNB2 (0.56) | TBXAS1FFAR4KMT2ACHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153214-A | Treating cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0493324-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |