SCHEMBL9710137

SCHEMBL9710137

NC(=S)SCCCC(=O)O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.75
TSHR P16473 4/20 0.45
LMNA P02545 5/20 0.43
SLC22A6 Q4U2R8 1/20 0.43
KMT2A Q03164 3/20 0.42
THRB P10828 2/20 0.42
BLM P54132 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
GABRR3 A8MPY1 1/20 0.42
GABRP O00591 1/20 0.42
GABRD O14764 1/20 0.42
HDAC3 O15379 1/20 0.42
GABBR2 O75899 1/20 0.42
GABRA1 P14867 1/20 0.42
GABRB1 P18505 1/20 0.42
GABRG2 P18507 1/20 0.42
GABRR1 P24046 1/20 0.42
GABRB3 P28472 1/20 0.42
GABRR2 P28476 1/20 0.42
SLC6A1 P30531 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31427507 0.84 CYP1A2 (0.95) CYP1A2TSHRLMNASLC22A6KMT2A
SCHEMBL10956219 0.84 CYP1A2 (0.95) CYP1A2TSHRLMNASLC22A6KMT2A
SCHEMBL11880033 0.81 TSHR (0.48) CYP1A2TSHRLMNASLC22A6KMT2A
SCHEMBL11856427 0.81 TSHR (0.48) CYP1A2TSHRLMNASLC22A6KMT2A
Octanoic Acid SCHEMBL27497933 0.79 GPR84 (0.59) CYP1A2TSHRLMNASLC22A6KMT2A
SCHEMBL4280583 0.77 CYP1A2 (0.54) CYP1A2TSHRLMNASLC22A6KMT2A
SCHEMBL5270528 0.77 CYP1A2 (0.52) CYP1A2TSHRALDH1A1HSD17B10TDP1
Ammonia Solution, Strong SCHEMBL8862732 0.75 CYP1A2 (0.50) CYP1A2ALDH1A1HSD17B10TDP1
SCHEMBL3414313 0.75 CYP1A2 (0.50) CYP1A2ALDH1A1HSD17B10TDP1
SCHEMBL31613051 0.75 CYP1A2 (0.50) CYP1A2ALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992021666-A1 ANGIOTENSIN II RECEPTOR ANTAGONIST THIAZOLE DEVIVATIVES LABORATOIRES UPSA (FR) 1992-12-10 WO disclosed