Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455772 | 0.84 | CYP1A2 (0.65) | TSHRCYP1A2LMNASLC22A6NFKB1 | |
| SCHEMBL15974606 | 0.83 | TSHR (0.48) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL4455371 | 0.82 | GPR84 (0.63) | TSHRCYP1A2LMNASLC22A6ALDH1A1 | |
| SCHEMBL9710137 | 0.81 | CYP1A2 (0.75) | TSHRCYP1A2LMNASLC22A6NFKB1 | |
| SCHEMBL4731418 | 0.81 | CYP1A2 (0.50) | TSHRCYP1A2SLC22A6ALDH1A1KMT2A | |
| SCHEMBL28870876 | 0.77 | LMNA (0.50) | TSHRCYP1A2LMNASLC22A6NFKB1 | |
| SCHEMBL20472265 | 0.76 | TSHR (0.45) | TSHRCYP1A2LMNASLC22A6NFKB1 | |
| SCHEMBL11880033 | 0.75 | TSHR (0.48) | TSHRCYP1A2LMNASLC22A6NFKB1 | |
| SCHEMBL1820452 | 0.75 | TSHR (0.54) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL16558618 | 0.75 | CYP1A2 (0.60) | TSHRCYP1A2LMNASLC22A6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976769-A | INSECTICIDE | AIRWICK INDUSTRIES, INC. (US) | 1976-08-24 | — | — | US | disclosed |