Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528178 | 0.80 | EPHX2 (0.39) | MAOAMAOBACHEPARP1 | |
| SCHEMBL8526843 | 0.76 | IKBKB (0.37) | MAOAMAOB | |
| SCHEMBL9786984 | 0.76 | ACHE (0.41) | ACHEL3MBTL1CYP19A1AADAT | |
| SCHEMBL9710193 | 0.76 | CDK5 (0.49) | MAOAMAOB | |
| SCHEMBL8526839 | 0.76 | HPGD (0.39) | MAOAMAOB | |
| SCHEMBL1728115 | 0.69 | TOP1 (0.43) | ACHEL3MBTL1 | |
| SCHEMBL30825444 | 0.69 | CDK5 (0.56) | ACHECYP19A1PARP1 | |
| SCHEMBL9475835 | 0.69 | CDK5 (0.56) | ACHECYP19A1PARP1 | |
| SCHEMBL20573209 | 0.69 | DRD2 (0.45) | ACHE | |
| SCHEMBL10861507 | 0.68 | KDM4E (0.42) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021668-A1 | BENZOTHIAZEPINONES AND THEIR USE AS ANTICONVULSANTS | THE BOOTS COMPANY PLC (GB) | 1992-12-10 | — | — | WO | disclosed |