Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24848568 | 0.75 | KDM4E (0.57) | KDM4EHSD17B10MAPTPOLBTP53 | |
| SCHEMBL9773340 | 0.72 | PTPN2 (0.46) | KDM4EHSD17B10MAPTPOLBLMNA | |
| SCHEMBL2056931 | 0.70 | ALDH1A1 (0.72) | KDM4EHSD17B10MAPTTP53LMNA | |
| SCHEMBL29670121 | 0.70 | ALDH1A1 (0.72) | KDM4EHSD17B10MAPTTP53LMNA | |
| SCHEMBL2783065 | 0.69 | ALDH1A1 (0.59) | KDM4EMAPTPOLBTP53LMNA | |
| SCHEMBL29724622 | 0.69 | ALDH1A1 (0.59) | KDM4EMAPTPOLBTP53LMNA | |
| SCHEMBL24848565 | 0.69 | MAPT (0.53) | KDM4EHSD17B10MAPTPOLBTP53 | |
| SCHEMBL29860539 | 0.67 | ALDH1A1 (1.00) | KDM4EHSD17B10MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL351486 | 0.67 | ALDH1A1 (1.00) | KDM4EHSD17B10MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1312896 | 0.67 | CSNK2A2 (0.55) | KDM4EHSD17B10MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022552-A1 | IMIDAZO[1,5-a]QUINOXALINES | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | claimed |