Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL9388302 | 0.81 | LMNA (0.50) | MTNR1AMTNR1BFFAR1LMNAGAA | |
| Propionic Acid SCHEMBL28882997 | 0.79 | MTNR1A (0.45) | MTNR1AMTNR1BLMNAGAAPOLB | |
| SCHEMBL4438868 | 0.75 | MTNR1A (0.43) | MTNR1AMTNR1BGAAPOLBCYP1A2 | |
| SCHEMBL18886541 | 0.74 | LMNA (0.47) | MTNR1AMTNR1BLMNAGAAPOLB | |
| Propanol SCHEMBL6407074 | 0.74 | LMNA (0.47) | MTNR1AMTNR1BLMNAGAAPOLB | |
| Alcohol SCHEMBL4086513 | 0.74 | LMNA (0.50) | MTNR1AMTNR1BLMNAGAAPOLB | |
| Acetic Acid SCHEMBL27465373 | 0.74 | MTNR1A (0.53) | MTNR1AMTNR1BLMNAGAAPOLB | |
| SCHEMBL15709 | 0.74 | LMNA (0.52) | MTNR1AMTNR1BLMNAGAAPOLB | |
| Benzene SCHEMBL28097669 | 0.74 | LMNA (0.52) | MTNR1AMTNR1BLMNAGAAPOLB | |
| SCHEMBL167127 | 0.74 | LMNA (0.52) | MTNR1AMTNR1BLMNAGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992019275-A2 | COSMETIC COMPOSITIONS | THE PROCTER & GAMBLE_COMPANY (US) | 1992-11-12 | — | — | WO | disclosed |
| WO-1992019216-A1 | SKIN AND HAIR-CARE GEL COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1992-11-12 | — | — | WO | disclosed |