Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 10/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9376712 | 0.84 | GABRG2 (0.45) | GABRG2GABRB3GABRA5GABRA2GABRA1 | |
| SCHEMBL29652624 | 0.84 | MEN1 (0.39) | GABRG2GABRB3GABRA5GABRA2GABRA1 | |
| SCHEMBL2232627 | 0.78 | GABRG2 (0.58) | GABRG2GABRB3GABRA5GABRA2GABRA1 | |
| SCHEMBL8558986 | 0.72 | GABRG2 (0.51) | GABRG2GABRB3GABRA5GABRA2GABRA1 | |
| SCHEMBL16935799 | 0.69 | GABRG2 (0.51) | GABRG2GABRB3GABRA5GABRA2GABRA1 | |
| SCHEMBL7327996 | 0.69 | GABRG2 (0.53) | GABRG2GABRB3GABRA5GABRA2GABRA1 | |
| SCHEMBL17651945 | 0.68 | GABRG2 (0.61) | GABRG2GABRB3GABRA5GABRA2GABRA1 | |
| SCHEMBL9260791 | 0.68 | GABRG2 (0.67) | GABRG2GABRB3GABRA5GABRA2GABRA1 | |
| SCHEMBL4963197 | 0.68 | TP53 (0.58) | GABRG2GABRB3GABRA5GABRA2GABRA1 | |
| SCHEMBL2236417 | 0.68 | GABRG2 (0.60) | GABRG2GABRB3GABRA5GABRA2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022552-A1 | IMIDAZO[1,5-a]QUINOXALINES | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |