SCHEMBL9710679

SCHEMBL9710679

Cn1c(C#N)c(Cl)n(-c2ccc(Cl)c(Cl)c2)c1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.41
ALDH1A1 P00352 4/20 0.41
USP2 O75604 1/20 0.41
HSD17B10 Q99714 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NOTUM Q6P988 1/20 0.38
SLC6A2 P23975 2/20 0.37
SLC6A4 P31645 2/20 0.37
RXFP1 Q9HBX9 1/20 0.36
TP53 P04637 1/20 0.36
HTT P42858 1/20 0.36
GFER P55789 1/20 0.36
KMT2A Q03164 2/20 0.35
BCL2A1 Q16548 2/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 2/20 0.35
BCL2 P10415 1/20 0.35
ALOX12 P18054 1/20 0.35
BID P55957 1/20 0.35
RAD51 Q06609 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9710614 0.90 MAPT (0.42) MAPTALDH1A1USP2HSD17B10L3MBTL1
SCHEMBL9710787 0.83 GSK3A (0.49) MAPTALDH1A1L3MBTL1RXFP1HTT
SCHEMBL9710970 0.82 GSK3A (0.45) MAPTALDH1A1RXFP1HTTKMT2A
SCHEMBL9710845 0.81 GSK3A (0.46) MAPTALDH1A1HSD17B10TP53HTT
SCHEMBL9710619 0.80 GSK3B (0.46) ALDH1A1RXFP1KMT2A
SCHEMBL9710731 0.77 GSK3A (0.50) RAD51PTGS2
SCHEMBL11266774 0.75 NOTUM (0.38) MAPTALDH1A1L3MBTL1NOTUMSLC6A2
SCHEMBL9711118 0.75 MGLL (0.41) MAPTALDH1A1NOTUMTP53KMT2A
SCHEMBL9710903 0.74 POLB (0.44) ALDH1A1L3MBTL1PTGS2
SCHEMBL9710822 0.72 GSK3A (0.50) MAPTALDH1A1RXFP1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992021662-A1 POSSIBLY CONDENSED PHENYLIMIDAZOLONES AND PYRIMIDINONES AS HERBICIDES; INTERMEDIATES DOWELANCO (US) 1992-12-10 WO disclosed
US-5153316-A Post and preemergence herbicides DOWELANCO 1992-10-06 US disclosed