Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 5/20 | 0.35 |
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | DRD5 | P21918 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380028 | 0.95 | PPARG (0.41) | BCHEACHEF10DRD2DRD3 | |
| SCHEMBL8503102 | 0.88 | BCHE (0.46) | BCHEACHEHTR1DHTR1AHTR1B | |
| SCHEMBL30665126 | 0.82 | DRD2 (0.42) | HTR1DDRD2DRD3DRD4DRD1 | |
| SCHEMBL2984151 | 0.82 | DRD2 (0.42) | HTR1DDRD2DRD3DRD4DRD1 | |
| Hydrogen Sulfide SCHEMBL28795253 | 0.80 | DRD2 (0.41) | HTR1DDRD2DRD3DRD4DRD1 | |
| SCHEMBL14032144 | 0.76 | DRD2 (0.41) | HTR1DHTR1AHTR1BDRD2DRD3 | |
| Biphenyl SCHEMBL4350539 | 0.76 | DRD2 (0.39) | HTR1DDRD2DRD3DRD4DRD1 | |
| SCHEMBL6934553 | 0.73 | MAPT (0.43) | HTR1DDRD2DRD3DRD4DRD1 | |
| SCHEMBL5178160 | 0.72 | CA1 (0.56) | HTR1DHTR1AHTR1BDRD2DRD3 | |
| Iodide SCHEMBL8735164 | 0.71 | DRD2 (0.40) | HTR1DDRD2DRD3DRD4DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020642-A1 | BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-11-26 | — | — | WO | disclosed |