Isonicotinonitrile

Isonicotinonitrile

SCHEMBL9710828

N#Cc1ccncc1.O=C(c1ccccc1)c1ccncc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.71
MEN1 O00255 1/20 0.71
ALDH1A1 P00352 5/20 0.50
CYP1A2 P05177 2/20 0.50
CYP3A4 P08684 2/20 0.50
CYP2D6 P10635 2/20 0.50
CYP2C9 P11712 2/20 0.50
HPGD P15428 2/20 0.50
CYP2C19 P33261 2/20 0.50
PLOD2 O00469 1/20 0.50
PLOD3 O60568 1/20 0.50
PLOD1 Q02809 1/20 0.50
HIF1A Q16665 1/20 0.50
LMNA P02545 2/20 0.47
LTA4H P09960 1/20 0.47
PKM P14618 2/20 0.46
NAPRT Q6XQN6 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
MAPT P10636 1/20 0.45
TSHR P16473 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzophenone SCHEMBL8986537 0.98 KMT2A (0.68) KMT2AMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL17338820 0.87 LTA4H (0.57) KMT2AMEN1CYP3A4CYP2D6LMNA
Benzophenone SCHEMBL9307169 0.85 ALDH1A1 (0.64) KMT2AMEN1ALDH1A1HPGDLMNA
SCHEMBL229650 0.84 KMT2A (1.00) KMT2AMEN1ALDH1A1CYP1A2CYP3A4
Acetophenone SCHEMBL9158734 0.84 ALDH1A1 (0.49) KMT2AMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL3215328 0.83 ALDH1A1 (0.61) KMT2AMEN1ALDH1A1HPGDLMNA
SCHEMBL12551894 0.79 KMT2A (0.87) KMT2AMEN1ALDH1A1CYP1A2CYP3A4
Benzophenone SCHEMBL4019789 0.78 KMT2A (0.86) KMT2AMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL13063666 0.78 MAPT (0.60) KMT2AMEN1ALDH1A1LMNAPKM
SCHEMBL13063665 0.78 MAPT (0.60) KMT2AMEN1ALDH1A1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992019596-A2 PROCESSES FOR PRODUCING α-PYRIDYL CARBINOLS REILLY INDUSTRIES, INC. (US) 1992-11-12 WO disclosed