Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710913 | 1.00 | AKR1C3 (0.53) | AKR1C3TBXAS1MAPK1PKMMEN1 | |
| SCHEMBL2462983 | 0.78 | AKR1C3 (0.82) | AKR1C3TBXAS1HTTALDH1A1GLA | |
| SCHEMBL2462984 | 0.78 | AKR1C3 (0.82) | AKR1C3TBXAS1HTTALDH1A1GLA | |
| SCHEMBL1088771 | 0.75 | AKR1C3 (0.55) | AKR1C3TBXAS1MEN1KMT2AHTT | |
| SCHEMBL1088772 | 0.75 | AKR1C3 (0.55) | AKR1C3TBXAS1MEN1KMT2AHTT | |
| SCHEMBL1089451 | 0.74 | AKR1C3 (0.53) | AKR1C3TBXAS1MEN1KMT2AHTT | |
| SCHEMBL1088972 | 0.74 | AKR1C3 (0.53) | AKR1C3TBXAS1MEN1KMT2AHTT | |
| SCHEMBL1088970 | 0.74 | AKR1C3 (0.53) | AKR1C3TBXAS1MEN1KMT2AHTT | |
| SCHEMBL1089453 | 0.74 | AKR1C3 (0.53) | AKR1C3TBXAS1MEN1KMT2AHTT | |
| SCHEMBL1089129 | 0.73 | AKR1C3 (0.51) | AKR1C3TBXAS1MAPK1PKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992015625-A1 | POLYMERIC NITRONES HAVING AN ACRYLIC BACKBONE CHAIN | ALLIED-SIGNAL INC. (US) | 1992-09-17 | — | — | WO | disclosed |