Pyrophosphoric Acid

SCHEMBL9711007

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nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MMP1 MMP13 MMP7 MMP8 pol rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	FDPS	P14324	1/20	0.67

▸	BLM	P54132	1/20	0.67

▸	TDP1	Q9NUW8	1/20	0.67

▸	PPARD	Q03181	2/20	0.46

▸	BTN3A1	O00481	4/20	0.40

▸	ALDH1A1	P00352	1/20	0.40

▸	TSHR	P16473	1/20	0.40

▸	LPAR3	Q9UBY5	3/20	0.39

▸	LPAR1	Q92633	2/20	0.39

▸	LPAR2	Q9HBW0	2/20	0.39

▸	CA2	P00918	1/20	0.35

▸	SMPD1	P17405	2/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Pyrophosphoric Acid SCHEMBL2443720	1.00	FDPS (0.67)	FDPSBLMTDP1PPARDBTN3A1
Pyrophosphoric Acid SCHEMBL28299705	0.97	FDPS (0.62)	FDPSBLMTDP1PPARDBTN3A1
Pyrophosphoric Acid SCHEMBL2426695	0.90	FDPS (0.71)	FDPSBLMTDP1PPARDBTN3A1
Pyrophosphoric Acid SCHEMBL5822274	0.90	FDPS (0.71)	FDPSBLMTDP1PPARDBTN3A1
Pyrophosphoric Acid SCHEMBL8761218	0.87	FDPS (0.67)	FDPSBLMTDP1PPARDBTN3A1
Pyrophosphoric Acid SCHEMBL28586076	0.84	FDPS (0.48)	FDPSBLMTDP1PPARDBTN3A1
Pyrophosphoric Acid SCHEMBL31372362	0.84	FDPS (0.62)	FDPSBLMTDP1PPARDBTN3A1
Pyrophosphoric Acid SCHEMBL8837385	0.83	FDPS (0.71)	FDPSBLMTDP1PPARDBTN3A1
Pyrophosphoric Acid SCHEMBL2575783	0.83	FDPS (0.71)	FDPSBLMTDP1PPARDBTN3A1
Pyrophosphoric Acid SCHEMBL3910021	0.82	FDPS (0.83)	FDPSBLMTDP1PPARDBTN3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1992017624-A1	FORMALDEHYDE-FREE BATH FOR THE CURRENTLESS DEPOSITION OF COPPER, PROCESS AND THE USE OF POLYETHYLENE IMINES IN FORMALDEHYDE-FREE BATHS	SCHERING AKTIENGESELLSCHAFT (DE)	1992-10-15	—	—	WO	disclosed