Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | BTN3A1 | O00481 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL9711007 | 0.97 | FDPS (0.67) | FDPSBLMTDP1PPARDBTN3A1 | |
| Pyrophosphoric Acid SCHEMBL2443720 | 0.97 | FDPS (0.67) | FDPSBLMTDP1PPARDBTN3A1 | |
| Pyrophosphoric Acid SCHEMBL2426695 | 0.87 | FDPS (0.71) | FDPSBLMTDP1PPARDBTN3A1 | |
| Pyrophosphoric Acid SCHEMBL5822274 | 0.87 | FDPS (0.71) | FDPSBLMTDP1PPARDBTN3A1 | |
| Pyrophosphoric Acid SCHEMBL8761218 | 0.84 | FDPS (0.67) | FDPSBLMTDP1PPARDBTN3A1 | |
| Pyrophosphoric Acid SCHEMBL1001202 | 0.83 | FDPS (0.91) | FDPSBLMTDP1BTN3A1SMPD1 | |
| Pyrophosphoric Acid SCHEMBL8535679 | 0.83 | FDPS (0.91) | FDPSBLMTDP1BTN3A1SMPD1 | |
| Pyrophosphoric Acid SCHEMBL9751415 | 0.83 | FDPS (0.91) | FDPSBLMTDP1BTN3A1SMPD1 | |
| Pyrophosphoric Acid SCHEMBL2348555 | 0.83 | FDPS (0.91) | FDPSBLMTDP1BTN3A1SMPD1 | |
| Pyrophosphoric Acid SCHEMBL5141446 | 0.83 | FDPS (0.91) | FDPSBLMTDP1BTN3A1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105861507-B | A kind of rice specificity promoter Psub6 and its application by the expression of water logging stress-inducing | 安徽省农业科学院水稻研究所 | 2019-05-10 | — | — | CN | disclosed |