SCHEMBL9711103

SCHEMBL9711103

C#CCOc1cc(-n2c(Cl)c(C#N)n(C)c2=O)c(F)cc1Br

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CGAS Q8N884 1/20 0.32
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9710891 0.90 PGK1 (0.36)
SCHEMBL9710864 0.82 PGK1 (0.37)
SCHEMBL9710824 0.80 MEN1 (0.31) CGASMEN1POLBKMT2A
SCHEMBL9710767 0.78 PGK1 (0.36)
SCHEMBL9711090 0.78 PGK1 (0.37)
SCHEMBL10577120 0.76 CGAS (0.32) CGASMEN1POLBKMT2A
SCHEMBL9710890 0.74 PRKDC (0.35) MEN1KMT2A
SCHEMBL9710810 0.73 PGK1 (0.36)
SCHEMBL9710897 0.72 PPOX (0.32)
SCHEMBL9710770 0.72 PPOX (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992021662-A1 POSSIBLY CONDENSED PHENYLIMIDAZOLONES AND PYRIMIDINONES AS HERBICIDES; INTERMEDIATES DOWELANCO (US) 1992-12-10 WO disclosed
US-5153316-A Post and preemergence herbicides DOWELANCO 1992-10-06 US disclosed