Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | RNF4 | P78317 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131683 | 0.78 | TP53 (0.66) | TP53TDP1MEN1KMT2ANR1I2 | |
| SCHEMBL3695063 | 0.78 | TP53 (0.66) | TP53TDP1MEN1KMT2ANR1I2 | |
| Ether SCHEMBL11040576 | 0.76 | TP53 (0.63) | TP53RNF4TDP1MEN1KMT2A | |
| SCHEMBL55713 | 0.74 | NPC1 (0.61) | TP53MEN1KMT2AMTNR1BMTNR1A | |
| SCHEMBL8538067 | 0.74 | NPC1 (0.61) | TP53MEN1KMT2AMTNR1BMTNR1A | |
| SCHEMBL7088596 | 0.71 | NPC1 (0.66) | TP53NPC1RAB9A | |
| SCHEMBL11659986 | 0.71 | TP53 (0.62) | TP53TDP1MEN1KMT2ANR1I2 | |
| SCHEMBL11653949 | 0.70 | TP53 (0.66) | TP53RNF4TDP1MEN1KMT2A | |
| SCHEMBL11161883 | 0.70 | MTNR1B (0.74) | TP53MTNR1BMTNR1AALDH1A1 | |
| SCHEMBL11787571 | 0.69 | RNF4 (0.63) | RNF4MTNR1BMTNR1AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020684-A1 | HERBICIDAL OXATRICYCLIC ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-11-26 | — | — | WO | disclosed |