Dimethylamine

Dimethylamine

SCHEMBL3965554

CNC.Cc1ccccc1C(=O)C(=O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC5 P28715 1/20 0.56
FEN1 P39748 1/20 0.56
HPGD P15428 4/20 0.53
POLB P06746 2/20 0.52
CYP2C19 P33261 1/20 0.52
KDM4E B2RXH2 2/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
GAA P10253 1/20 0.45
MYC P01106 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HSD17B10 Q99714 1/20 0.44
KCNK3 O14649 1/20 0.44
KCNK9 Q9NPC2 1/20 0.44
GPR52 Q9Y2T5 1/20 0.44
MEN1 O00255 1/20 0.43
AKR1B10 O60218 1/20 0.43
TRPA1 O75762 1/20 0.43
ABCB11 O95342 1/20 0.43
DHFR P00374 1/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL166031 0.94 ERCC5 (0.57) ERCC5FEN1HPGDPOLBCYP2C19
SCHEMBL9711362 0.94 ERCC5 (0.57) ERCC5FEN1HPGDPOLBCYP2C19
Benzoyl Formic Acid SCHEMBL4889317 0.86 CES2 (0.50) ERCC5FEN1HPGDPOLBCYP2C19
Methyl Benzoate SCHEMBL30404125 0.82 TSHR (0.63) ERCC5FEN1HPGDSMN1; SMN2GAA
SCHEMBL166603 0.82 HPGD (0.54) ERCC5FEN1HPGDPOLBKDM4E
SCHEMBL29425530 0.82 HPGD (0.54) ERCC5FEN1HPGDPOLBKDM4E
Toluic Acid SCHEMBL7244386 0.81 ALDH1A1 (0.55) ERCC5FEN1HPGDPOLBKDM4E
SCHEMBL29387814 0.81 ERCC5 (0.46) ERCC5FEN1HPGDPOLBCYP2C19
Dimethylamine SCHEMBL3307126 0.80 NPC1 (0.46) ERCC5FEN1HPGDPOLBKDM4E
SCHEMBL1191330 0.79 HPGD (0.48) ERCC5FEN1HPGDPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2134673-A1 IMPROVED PROCESS FOR PREPARING O-CHLOROMETHYLPHENYLGLYOXYLIC ESTERS, IMPROVED PROCESS FOR PREPARING (E)-2-(2-CHLOROMETHYLPHENYL)-2-ALKOXIMINOACETIC ESTERS, AND NOVEL INTERMEDIATES FOR THEIR PREPARATION DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2009-12-23 EP disclosed
WO-2009037230-A2 IMPROVED PROCESS FOR PREPARING (E)-2-(2-CHLOROMETHYLPHENYL)-2-ALKOXIMINOACETIC ESTERS DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2009-03-26 WO disclosed
WO-2008125592-A1 IMPROVED PROCESS FOR PREPARING O-CHLOROMETHYLPHENYLGLYOXYLIC ESTERS, IMPROVED PROCESS FOR PREPARING (E)-2-(2-CHLOROMETHYLPHENYL)-2-ALKOXIMINOACETIC ESTERS, AND NOVEL INTERMEDIATES FOR THEIR PREPARATION DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2008-10-23 WO disclosed