Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13518302 | 0.81 | ALDH1A1 (0.47) | MPLKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL10231835 | 0.81 | KMT2A (0.45) | KMT2AALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL14453590 | 0.81 | KMT2A (0.57) | KMT2AALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL4882116 | 0.80 | PKM (0.51) | KMT2AALDH1A1LMNAMEN1L3MBTL1 | |
| SCHEMBL13564402 | 0.78 | KMT2A (0.45) | MPLKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL12556808 | 0.78 | BRD4 (0.46) | MPLKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL13518990 | 0.78 | ALDH1A1 (0.50) | MPLKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL15423698 | 0.77 | SMN1; SMN2 (0.40) | KMT2AALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL153566 | 0.76 | PKM (0.56) | KMT2AALDH1A1LMNAMEN1L3MBTL1 | |
| SCHEMBL343857 | 0.76 | KMT2A (0.41) | MPLKMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279477-B1 | CARBONYLATION PROCESS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-05-06 | — | — | EP | disclosed |
| EP-0168876-B1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS OF HYDROXY SULFONATES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-08-16 | — | — | EP | disclosed |
| EP-0279477-A1 | Carbonylation process | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-08-24 | — | — | EP | disclosed |
| EP-0168876-A2 | Process for the preparation of carboxylic acid esters of hydroxy sulfonates | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-01-22 | — | — | EP | disclosed |