Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 15/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 15/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175712 | 0.85 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1GRM2CTSDLMNA | |
| SCHEMBL481139 | 0.84 | CYSLTR1 (0.53) | CYSLTR2CYSLTR1GRM2CTSDLMNA | |
| SCHEMBL9177982 | 0.83 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL9637415 | 0.80 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1GRM2CTSDLMNA | |
| SCHEMBL9173919 | 0.80 | CYSLTR1 (0.64) | CYSLTR2CYSLTR1GRM2CTSD | |
| SCHEMBL9711384 | 0.80 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL9173547 | 0.79 | GRM2 (0.68) | CYSLTR2CYSLTR1GRM2CTSDLMNA | |
| SCHEMBL9176134 | 0.79 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL9181645 | 0.78 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1GRM2CTSDLMNA | |
| SCHEMBL9177346 | 0.78 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288189-B1 | IMPROVEMENTS IN OR RELATING TO LEUKOTRIENE ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1992-11-11 | — | — | EP | claimed |
| EP-0288189-A1 | Improvements in or relating to leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1988-10-26 | — | — | EP | claimed |
| EP-0288189-B1 | IMPROVEMENTS IN OR RELATING TO LEUKOTRIENE ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1992-11-11 | — | — | EP | disclosed |
| US-4853398-A | ANTIALLERGENS | ELI LILLY AND COMPANY (US) | 1989-08-01 | — | — | US | disclosed |
| EP-0288189-A1 | Improvements in or relating to leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1988-10-26 | — | — | EP | disclosed |