Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17070910 | 0.78 | MAPT (0.57) | MAPTGAAALDH1A1HPGDPOLB | |
| SCHEMBL1177037 | 0.78 | MAPT (0.57) | MAPTGAAALDH1A1HPGDPOLB | |
| SCHEMBL449180 | 0.77 | MAPT (0.82) | MAPTGAAALDH1A1HPGDPOLB | |
| SCHEMBL562614 | 0.73 | MAPT (1.00) | MAPTGAAALDH1A1HPGDPOLB | |
| SCHEMBL11170815 | 0.72 | MAPT (0.50) | MAPTGAAALDH1A1HPGDPOLB | |
| SCHEMBL657291 | 0.71 | CTRB1 (0.68) | MAPTGAAALDH1A1HPGDKMT2A | |
| SCHEMBL9541619 | 0.71 | CTRB1 (0.68) | MAPTGAAALDH1A1HPGDKMT2A | |
| SCHEMBL5964906 | 0.71 | MAPT (0.65) | MAPTGAAALDH1A1HPGDPOLB | |
| SCHEMBL5386997 | 0.71 | MAPT (0.59) | MAPTGAAALDH1A1HPGDKMT2A | |
| SCHEMBL10500501 | 0.71 | MAPT (0.50) | MAPTGAAALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992019588-A1 | NEW AMIDRAZONE DERIVATES, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS LIPOXYGENASE INHIBITORS | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1992-11-12 | — | — | WO | disclosed |