SCHEMBL657291

SCHEMBL657291

O=C1CC(c2ccccc2)CC(=O)O1

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 1/20 0.68
GAA P10253 3/20 0.59
MAPT P10636 3/20 0.59
CTRC Q99895 1/20 0.50
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
MAP1LC3B Q9GZQ8 1/20 0.46
BRD4 O60885 3/20 0.46
MAPK1 P28482 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ALDH1A1 P00352 4/20 0.44
ALDH2 P05091 1/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
USP2 O75604 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9541619 1.00 CTRB1 (0.68) CTRB1GAAMAPTCTRCMEN1
SCHEMBL10017608 0.88 CTRB1 (0.53) CTRB1GAAMAPTCTRCMAP1LC3B
SCHEMBL658941 0.88 CTRB1 (0.56) CTRB1GAAMAPTCTRCMEN1
SCHEMBL12595245 0.86 PLAU (0.59) CTRB1GAAMAPTCTRCMEN1
SCHEMBL16535401 0.83 CTRB1 (0.55) CTRB1GAAMAPTCTRCMEN1
SCHEMBL16535402 0.83 CTRB1 (0.55) CTRB1GAAMAPTCTRCMEN1
SCHEMBL10017611 0.82 CTRB1 (0.49) CTRB1GAAMAPTCTRCMEN1
SCHEMBL9857770 0.82 CTRB1 (0.54) CTRB1GAAMAPTCTRCMEN1
SCHEMBL657720 0.78 BRD4 (0.49) CTRB1GAAMAPTMEN1KMT2A
SCHEMBL2471171 0.78 MAP1LC3B (0.50) CTRB1MAPTMEN1KMT2AMAP1LC3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798627-A Method for preparing hydroxyl-terminated high molecular polyester polyol without metal catalyst and polyester polyol 北京高盟新材料股份有限公司 2025-04-11 CN claimed
CN-118852022-B Gemini quaternary ammonium salt antibacterial agent, preparation thereof and application thereof in antibacterial polyester synthesis 浙江大学 2025-03-28 CN claimed
CN-118852022-A Gemini quaternary ammonium salt antibacterial agent, preparation thereof and application thereof in antibacterial polyester synthesis 浙江大学 2024-10-29 CN claimed
US-11912818-B2 Method for synthesizing aromatic-aliphatic copolyester without catalyst and product thereof ZHEJIANG UNIVERSITY (CN) 2024-02-27 US claimed
CN-117199523-A Electrolyte, secondary battery and electric equipment 欣旺达动力科技股份有限公司 2023-12-08 CN claimed
US-20230391948-A1 METHOD FOR SYNTHESIZING AROMATIC-ALIPHATIC COPOLYESTER WITHOUT CATALYST AND PRODUCT THEREOF ZHEJIANG UNIVERSITY (CN) 2023-12-07 US claimed
WO-2022148259-A1 METHOD FOR SYNTHESIZING AROMATIC-ALIPHATIC COPOLYESTER WITHOUT CATALYST, AND PRODUCT THEREOF 浙江大学 2022-07-14 WO claimed
CN-112831033-B Method for synthesizing aromatic-aliphatic copolyester without catalyst and product thereof 浙江大学 2022-03-22 CN claimed
CN-111978528-B Method for synthesizing aromatic polyester without catalyst and product thereof 浙江大学 2021-11-09 CN claimed
CN-112831033-A Method for synthesizing aromatic-aliphatic copolyester without catalyst and product thereof 浙江大学 2021-05-25 CN claimed
CN-111978528-A Method for synthesizing aromatic polyester without catalyst and product thereof 浙江大学 2020-11-24 CN claimed
US-9062155-B2 Organometallic catalyst and preparation thereof UNIVERSITY OF SYDNEY (AU) 2015-06-23 US claimed
US-20130331544-A1 ORGANOMETALLIC CATALYST AND PREPARATION THEREOF THE UNIVERSITY OF SYDNEY (AU) 2013-12-12 US claimed
US-8507708-B2 Organometallic catalyst and preparation thereof THE UNIVERSITY OF SYDNEY (AU) 2013-08-13 US claimed
US-20110319645-A1 ORGANOMETALLIC CATALYST AND PREPARATION THEREOF UNIVERSITY OF SYDNEY (AU) 2011-12-29 US claimed
WO-2010069000-A1 ORGANOMETALLIC CATALYST AND PREPARATION THEREOF THE UNIVERSITY OF SYDNEY (AU) 2010-06-24 WO claimed
CN-122071574-A Novel PEAT material 元素驱动(杭州)生物科技有限公司 2026-05-22 CN disclosed
WO-2025124564-A1 POLYESTER SYNTHESIS BASED ON ASPARTIC ACID MODIFICATION 元素驱动(杭州)生物科技有限公司 2025-06-19 WO disclosed
US-4255429-A HYPOTENSIVE AGENTS CIBA-GEIGY CORPORATION (US) 1981-03-10 US disclosed
EP-0009465-A1 N-(1-(4-amino-2-quinazolinyl)-3 or 4-piperidyl lactames, process for their preparation and pharmaceutical compositions containing them CIBA-GEIGY AG (CH) 1980-04-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110319645-A1 ORGANOMETALLIC CATALYST AND PREPARATION THEREOF CA2, CA1, CA3 CTRB1 2677/4885GAA 1670/4885MAPT 3303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.