Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711535 | 0.76 | KMT2A (0.43) | KMT2AALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL9711499 | 0.73 | KMT2A (0.40) | KMT2AALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL17673999 | 0.68 | KMT2A (0.71) | KMT2AALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL31588107 | 0.68 | KMT2A (0.71) | KMT2AALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL9711607 | 0.66 | KMT2A (0.44) | KMT2AALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL10620700 | 0.65 | TSHR (0.43) | KMT2AALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL195311 | 0.65 | ALDH1A1 (0.62) | KMT2AALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL17010761 | 0.65 | KDM4E (0.59) | KMT2AALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL2289848 | 0.65 | ALDH1A1 (0.61) | KMT2AALDH1A1SMN1; SMN2HTTNPC1 | |
| SCHEMBL6551442 | 0.65 | ALDH1A1 (0.61) | KMT2AALDH1A1SMN1; SMN2HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |