Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | HPD | P32754 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711666 | 0.89 | HPGD (0.45) | SMN1; SMN2MAPTHPGDHPDTDP1 | |
| SCHEMBL9711509 | 0.87 | HPGD (0.43) | SMN1; SMN2MAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL9711571 | 0.87 | FLT1 (0.41) | SMN1; SMN2MAPTLMNAALDH1A1HPGD | |
| SCHEMBL9711519 | 0.87 | TRPV1 (0.42) | SMN1; SMN2MAPTALDH1A1HPGDHPD | |
| SCHEMBL9711510 | 0.87 | MAPT (0.43) | SMN1; SMN2MAPTLMNAALDH1A1MAPK1 | |
| SCHEMBL9711462 | 0.86 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPTALDH1A1HPGDHPD | |
| SCHEMBL9711558 | 0.85 | HPD (0.41) | SMN1; SMN2MAPTALDH1A1HPGDHPD | |
| SCHEMBL9711544 | 0.84 | HPD (0.40) | SMN1; SMN2MAPTLMNAALDH1A1HPGD | |
| SCHEMBL9711492 | 0.81 | HPD (0.43) | SMN1; SMN2LMNAALDH1A1HPGDMAPK1 | |
| SCHEMBL9711701 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2MAPTALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |