Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27527269 | 0.87 | RAB9A (0.52) | CYP2C19HIF1ANPC1RAB9ACYP1A2 | |
| SCHEMBL1930180 | 0.79 | NPC1 (0.46) | CYP2C19NPC1RAB9AMAPTCYP1A2 | |
| SCHEMBL9711508 | 0.76 | CYP2C19 (0.60) | CYP2C19HIF1ARAB9APOLBMAPT | |
| SCHEMBL6231282 | 0.74 | ATM (0.52) | CYP2C19NPC1RAB9AMAPTCYP1A2 | |
| SCHEMBL1144525 | 0.73 | CYP2C19 (0.56) | CYP2C19HIF1APOLBMAPTCYP1A2 | |
| SCHEMBL11865312 | 0.73 | NPC1 (0.47) | CYP2C19NPC1RAB9APOLBMAPT | |
| SCHEMBL11863319 | 0.72 | NPC1 (0.53) | CYP2C19NPC1RAB9APOLBMAPT | |
| SCHEMBL7443634 | 0.72 | NPC1 (0.56) | CYP2C19NPC1RAB9APOLBMAPT | |
| SCHEMBL1878859 | 0.72 | KEAP1 (0.50) | NPC1RAB9AMAPTDRD2DRD4 | |
| SCHEMBL6958948 | 0.72 | KMT2A (0.54) | CYP2C19HIF1ANPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050738-B1 | NOVEL IMIDAZOLIDINONE DERIVATIVE, METHOD OF PRODUCING THE SAME AND METHOD OF PRODUCING OPTICALLY ACTIVE AMINO ACID | KANEKA CORP (JP) | 2013-07-10 | — | — | EP | disclosed |
| US-7947722-B2 | Imidazolidinone derivative, method of producing the same and method of producing optically active amino acid | KANEKA CORPORATION (JP) | 2011-05-24 | — | — | US | disclosed |
| US-20090209768-A1 | NOVEL IMIDAZOLIDINONE DERIVATIVE, METHOD OF PRODUCING THE SAME AND METHOD OF PRODUCING OPTICALLY ACTIVE AMINO ACID | KANEKA CORPORATION (JP) | 2009-08-20 | — | — | US | disclosed |
| EP-2050738-A1 | NOVEL IMIDAZOLIDINONE DERIVATIVE, METHOD OF PRODUCING THE SAME AND METHOD OF PRODUCING OPTICALLY ACTIVE AMINO ACID | Kaneka Corporation (JP) | 2009-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209768-A1 | NOVEL IMIDAZOLIDINONE DERIVATIVE, METHOD OF PRODUCING THE SAME AND METHOD OF PRODUCING OPTICALLY ACTIVE AMINO ACID | DAO, RCC2, AADAT | CYP2C19 1264/4885HIF1A 4345/4885NPC1 3635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.