Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPD | P32754 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711461 | 0.86 | HPD (0.42) | HPGDCYP1A2CYP3A4CYP2C19NPC1 | |
| SCHEMBL9711473 | 0.79 | HPD (0.43) | HPGDCYP1A2CYP3A4CYP2C19NPC1 | |
| SCHEMBL9711509 | 0.75 | HPGD (0.43) | HPGDCYP1A2CYP3A4CYP2C19NPC1 | |
| SCHEMBL9711483 | 0.74 | ALDH1A1 (0.40) | HPDPOLBALDH1A1 | |
| SCHEMBL9711516 | 0.74 | HPD (0.48) | HPGDCYP1A2CYP3A4CYP2C19NPC1 | |
| SCHEMBL9711467 | 0.74 | HPD (0.43) | CYP3A4NPC1HPDPOLBALDH1A1 | |
| SCHEMBL9711492 | 0.74 | HPD (0.43) | HPGDCYP1A2CYP3A4CYP2C19NPC1 | |
| SCHEMBL8011992 | 0.73 | HPD (0.43) | HPGDCYP1A2CYP3A4CYP2C19NPC1 | |
| SCHEMBL9711504 | 0.73 | SMN1; SMN2 (0.41) | HPGDCYP1A2CYP3A4CYP2C19NPC1 | |
| SCHEMBL9711480 | 0.73 | HPD (0.45) | HPDPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |