Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.30 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.30 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL558876 | 0.79 | ESR1 (0.34) | POLBNPSR1TSHRPSMB1IDH1 | |
| SCHEMBL6174489 | 0.73 | POLB (0.34) | POLBNPSR1TSHRESR1HSP90AA1 | |
| SCHEMBL620180 | 0.72 | TSHR (0.37) | POLBNPSR1TSHRPSMB5PSMB1 | |
| SCHEMBL8698153 | 0.72 | TSHR (0.37) | POLBNPSR1TSHRPSMB5PSMB1 | |
| SCHEMBL2703082 | 0.70 | MAPT (0.38) | NPSR1TSHRPSMB1IDH1RAB9A | |
| SCHEMBL1505859 | 0.68 | BCHE (0.39) | POLBNPSR1TSHRPSMB1 | |
| SCHEMBL8677952 | 0.68 | NOTUM (0.48) | POLBTSHR | |
| SCHEMBL27500883 | 0.68 | POLB (0.36) | POLBNPSR1TSHRPSMB5PSMB1 | |
| SCHEMBL10877381 | 0.68 | CES1 (0.42) | POLBNPSR1TSHRRAB9A | |
| SCHEMBL23732646 | 0.67 | PSMB1 (0.36) | POLBNPSR1TSHRPSMB1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510356-A1 | Polyethylene glycol protein conjugates | F. HOFFMANN-LA ROCHE AG (CH) | 1992-10-28 | — | — | EP | disclosed |