Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2703082 | 0.84 | MAPT (0.38) | TSHRMAPTHSD17B10L3MBTL1PSMB1 | |
| SCHEMBL620180 | 0.81 | TSHR (0.37) | BCHETSHRMAPTPOLBHSD17B10 | |
| SCHEMBL8698153 | 0.81 | TSHR (0.37) | BCHETSHRMAPTPOLBHSD17B10 | |
| SCHEMBL27500883 | 0.77 | POLB (0.36) | TSHRMAPTPOLBL3MBTL1PSMB1 | |
| SCHEMBL8677952 | 0.77 | NOTUM (0.48) | TSHRPOLBHSD17B10HPGDALDH1A1 | |
| SCHEMBL12634297 | 0.77 | TSHR (0.33) | TSHRPOLBNPSR1 | |
| SCHEMBL16670485 | 0.77 | ALDH1A1 (0.41) | TSHRMAPTCYP3A4L3MBTL1PSMB1 | |
| SCHEMBL3173808 | 0.76 | INMT (0.40) | BCHEACHEPARP1TSHRLMNA | |
| SCHEMBL23732646 | 0.76 | PSMB1 (0.36) | BCHETSHRMAPTPOLBHSD17B10 | |
| SCHEMBL558876 | 0.74 | ESR1 (0.34) | TSHRPOLBPSMB1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2340021-B1 | SUBSTITUTED PYRROLIDINE-2-CARBOXAMIDES | HOFFMANN LA ROCHE (CH) | 2012-11-07 | — | — | EP | claimed |
| WO-2001077078-A1 | NOVEL PYRIDONES AND THEIR USE AS MODULATORS OF SERINE HYDROLASE ENZYMES | DALHOUSIE UNIVERSITY (CA) | 2001-10-18 | — | — | WO | claimed |
| EP-0090600-B1 | METHOD FOR MOLDING CAPSULES | WARNER-LAMBERT COMPANY (US) | 1987-07-22 | — | — | EP | claimed |
| EP-0092908-A2 | Hydrophilic polymer composition for injection molding | WARNER-LAMBERT COMPANY (US) | 1983-11-02 | — | — | EP | claimed |
| US-4123281-A | Photographic silver halide color material containing fast-acting hardener and 2-pyrazolin-5-one coupler precursors | AGFA-GEVAERT N.V. (BE) | 1978-10-31 | — | — | US | claimed |
| CN-121666236-A | Use of pyridone carboxamide compounds for the treatment of type I neurofibromatosis related disorders | 正大天晴药业集团股份有限公司 | 2026-03-13 | — | — | CN | disclosed |
| CN-121666236-A | Use of pyridone carboxamide compounds for the treatment of type I neurofibromatosis related disorders | 正大天晴药业集团股份有限公司 | 2026-03-13 | — | — | CN | disclosed |
| WO-2025026307-A1 | USE OF PYRIDONE CARBOXAMIDE COMPOUND IN TREATMENT OF DISEASES ASSOCIATED WITH NEUROFIBROMATOSIS TYPE I | 正大天晴药业集团股份有限公司 | 2025-02-06 | — | — | WO | disclosed |
| WO-2025026307-A1 | USE OF PYRIDONE CARBOXAMIDE COMPOUND IN TREATMENT OF DISEASES ASSOCIATED WITH NEUROFIBROMATOSIS TYPE I | 正大天晴药业集团股份有限公司 | 2025-02-06 | — | — | WO | disclosed |
| US-20220356174-A1 | PYRIDIN-2-ONE COMPOUNDS USEFUL AS SMARCA2 ANTAGONISTS | Epizyme, Inc. (US) | 2022-11-10 | — | — | US | disclosed |
| CN-107033134-B | Bisamide compound containing pyridinium and 1,3, 4-oxadiazolyl and preparation method and application thereof | 贵州大学 | 2020-02-21 | — | — | CN | disclosed |
| CN-107033098-B | 1,3,4- oxadiazoles sulphur/oxygen ether compound of amide bond and preparation method and application | 贵州大学 | 2019-08-30 | — | — | CN | disclosed |
| US-4591475-A | INJECTION MOLDING HYDROPHILIC POLYMERS | WARNER-LAMBERT COMPANY (US) | 1986-05-27 | — | — | US | disclosed |
| EP-0092908-A2 | Hydrophilic polymer composition for injection molding | WARNER-LAMBERT COMPANY (US) | 1983-11-02 | — | — | EP | disclosed |
| EP-0090600-A2 | Method for molding capsules | WARNER-LAMBERT COMPANY (US) | 1983-10-05 | — | — | EP | disclosed |
| US-4268623-A | Photographic light-sensitive material having a carboxylic acid polymer antistatic layer | FUJI PHOTO FILM CO., LTD. (JP) | 1981-05-19 | — | — | US | disclosed |
| US-4139387-A | FOGGING AGENT | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1979-02-13 | — | — | US | disclosed |
| US-4055427-A | Process of hardening a silver halide photographic material with a 1-carbamoyloxypyridinium salt | AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |
| US-4055427-A | Process of hardening a silver halide photographic material with a 1-carbamoyloxypyridinium salt | AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |
| US-3873537-A | 1-Imidocarbonyl-2-(1H)-pyridones and method of preparing same | SQUIBB & SONS INC | 1975-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220356174-A1 | PYRIDIN-2-ONE COMPOUNDS USEFUL AS SMARCA2 ANTAGONISTS | SMARCC1, SMARCC2, SMARCE1 | BCHE 4160/4885ACHE 4758/4885PARP1 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.