Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxane SCHEMBL2947014 | 0.81 | TTR (0.43) | TSHRMEN1POLBKMT2A | |
| Oxirane SCHEMBL28302535 | 0.81 | TTR (0.33) | — | |
| SCHEMBL971171 | 0.81 | TSHR (0.43) | TSHR | |
| Dioxane SCHEMBL6069108 | 0.79 | TTR (0.40) | TSHRPOLB | |
| SCHEMBL1736341 | 0.78 | ALDH1A1 (0.40) | TSHRKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL124190 | 0.78 | — | — | |
| SCHEMBL30 | 0.78 | — | — | |
| SCHEMBL971173 | 0.77 | — | — | |
| Cyclohexane SCHEMBL8471239 | 0.75 | ADH1C (0.32) | ALDH1A1KMT2A | |
| Fluoride SCHEMBL2116095 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110003277-A1 | Dioxetane-Nanoparticle Assemblies For Energy Transfer Detection Systems, Methods Of Making The Assemblies, And Methods Of Using The Assemblies in Bioassays | APPLIED BIOSYSTEMS, LLC (US) | 2011-01-06 | — | — | US | disclosed |
| EP-1787365-A2 | DIOXETANE-NANOPARTICLE ASSEMBLIES FOR ENERGY TRANSFER DETECTION SYSTEMS, METHODS OF MAKING THE ASSEMBLIES, AND METHODS OF USING THE ASSEMBLIES IN BIOASSAYS | Applera Corporation (US) | 2007-05-23 | — | — | EP | disclosed |
| US-20060216768-A1 | Dioxetane-nanoparticle assemblies for energy transfer detection systems, methods of making the assemblies, and methods of using the assemblies in bioassays | APPLIED BIOSYSTEMS, LLC | 2006-09-28 | — | — | US | disclosed |
| WO-2006029302-A2 | DIOXETANE-NANOPARTICLE ASSEMBLIES FOR ENERGY TRANSFER DETECTION SYSTEMS, METHODS OF MAKING THE ASSEMBLIES, AND METHODS OF USING THE ASSEMBLIES IN BIOASSAYS | APPLERA CORPORATION (US) | 2006-03-16 | — | — | WO | disclosed |