Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23992099 | 0.81 | OPRM1 (0.49) | OPRM1HCAR2LPAR1LPAR3 | |
| SCHEMBL7551767 | 0.81 | MEN1 (0.49) | POLB | |
| SCHEMBL10638831 | 0.81 | OPRM1 (0.53) | OPRM1HCAR2LPAR1LPAR3 | |
| SCHEMBL9293279 | 0.80 | OPRM1 (0.50) | OPRM1HCAR2HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL1059565 | 0.80 | HCAR2 (0.53) | OPRM1HCAR2ALDH1A1HTTLPAR1 | |
| SCHEMBL27941408 | 0.80 | OPRM1 (0.52) | OPRM1HCAR2ALDH1A1LMNAHTT | |
| SCHEMBL1059944 | 0.80 | HCAR2 (0.53) | OPRM1HCAR2ALDH1A1HTTLPAR1 | |
| SCHEMBL11186607 | 0.78 | OPRM1 (0.51) | OPRM1HCAR2HPGDALDH1A1HTT | |
| SCHEMBL10639479 | 0.78 | OPRM1 (0.51) | OPRM1HCAR2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL9831112 | 0.77 | OPRM1 (0.50) | OPRM1HCAR2HTTLPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125726-B2 | IMPROVED PROCESS FOR PREPARING ALKYL ISOCYANATES | ENICHEM SYNTHESIS S.p.A. (IT) | 1992-09-09 | — | — | EP | claimed |
| EP-0125726-B1 | IMPROVED PROCESS FOR PREPARING ALKYL ISOCYANATES | ENICHEM SYNTHESIS S.p.A. (IT) | 1986-07-16 | — | — | EP | claimed |
| EP-0190466-B1 | PROCESS FOR THE PRODUCTION OF N-METHYLCARBAMATES | ENICHEM SYNTHESIS S.p.A. (IT) | 1990-11-28 | — | — | EP | disclosed |
| US-4659845-A | Process for the production of N-methylcarbamates | ENICHEM SINTESI S.P.A. (IT) | 1987-04-21 | — | — | US | disclosed |
| EP-0190466-A1 | Process for the production of N-Methylcarbamates | ENICHEM SYNTHESIS S.p.A. (IT) | 1986-08-13 | — | — | EP | disclosed |
| EP-0125726-A1 | Improved process for preparing alkyl isocyanates | ENICHEM SYNTHESIS S.p.A. (IT) | 1984-11-21 | — | — | EP | disclosed |