Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10639479 | 0.86 | OPRM1 (0.51) | OPRM1HCAR2KCNA5KCNA3LPAR1 | |
| SCHEMBL11186607 | 0.86 | OPRM1 (0.51) | OPRM1HCAR2KCNA5KCNA3LPAR1 | |
| SCHEMBL9831112 | 0.84 | OPRM1 (0.50) | OPRM1HCAR2KCNA5KCNA3LPAR1 | |
| SCHEMBL17550883 | 0.84 | OPRM1 (0.50) | OPRM1HCAR2KCNA5KCNA3LPAR1 | |
| Hydrochloric Acid SCHEMBL28345934 | 0.83 | OPRM1 (0.49) | OPRM1HCAR2KCNA5KCNA3LPAR1 | |
| SCHEMBL9828137 | 0.83 | HTT (0.56) | OPRM1HCAR2HPGDALDH1A1HTT | |
| SCHEMBL9308871 | 0.83 | NAAA (0.51) | OPRM1NAAAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL10638831 | 0.82 | OPRM1 (0.53) | OPRM1HCAR2KCNA5KCNA3LPAR1 | |
| SCHEMBL27941408 | 0.81 | OPRM1 (0.52) | OPRM1HCAR2KCNA5KCNA3LPAR1 | |
| SCHEMBL19750478 | 0.81 | OPRM1 (0.47) | OPRM1HCAR2KCNA5KCNA3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34722-E | Antiulcer agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| US-4578381-A | ANTIULCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-25 | — | — | US | disclosed |