Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712151 | 1.00 | SLC5A1 (0.41) | SLC5A1SLC5A2APPALDH1A1MAPK1 | |
| SCHEMBL9711921 | 0.98 | SLC5A1 (0.42) | SLC5A1SLC5A2APPALDH1A1MAPK1 | |
| SCHEMBL9014872 | 0.83 | SLC5A1 (0.43) | SLC5A1SLC5A2APPALDH1A1MAPK1 | |
| SCHEMBL9014900 | 0.83 | SLC5A1 (0.43) | SLC5A1SLC5A2APPALDH1A1MAPK1 | |
| SCHEMBL1652185 | 0.82 | CA12 (0.50) | ALDH1A1MAPK1USP2SMN1; SMN2MEN1 | |
| SCHEMBL9014656 | 0.81 | SLC5A1 (0.44) | SLC5A1SLC5A2APPALDH1A1MAPK1 | |
| SCHEMBL14004238 | 0.80 | RARB (0.41) | SLC5A1SLC5A2ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9705907 | 0.80 | HRH3 (0.42) | — | |
| SCHEMBL12926348 | 0.79 | APP (0.53) | APPALDH1A1LMNAL3MBTL1 | |
| SCHEMBL31316456 | 0.79 | THRB (0.50) | ALDH1A1MAPK1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091274-A | Modified polysiloxanes | NATIONAL SCIENCE COUNCIL (TW) | 1992-02-25 | — | — | US | disclosed |