SCHEMBL1652185

SCHEMBL1652185

C=CCOc1ccc(CCl)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
ALDH1A1 P00352 4/20 0.47
MAPT P10636 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
POLB P06746 2/20 0.46
USP2 O75604 1/20 0.46
CACNA1B Q00975 1/20 0.46
APBA1 Q02410 1/20 0.46
CYP2D6 P10635 1/20 0.45
NPC1 O15118 1/20 0.42
TP53 P04637 1/20 0.42
RAB9A P51151 1/20 0.42
KDM4E B2RXH2 2/20 0.42
HPGD P15428 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Diallyloxybenzene SCHEMBL302448 0.84 CA12 (0.63) CA12CA1CA2CA7CA9
SCHEMBL9711921 0.83 SLC5A1 (0.42) CA12CA1CA2CA7CA9
SCHEMBL826483 0.83 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL8418525 0.82 ALDH1A1 (0.47) CA12CA1CA2CA7CA9
SCHEMBL9712052 0.82 SLC5A1 (0.41) CA12CA1CA2CA7CA9
SCHEMBL9712151 0.82 SLC5A1 (0.41) CA12CA1CA2CA7CA9
SCHEMBL9504919 0.82 BCHE (0.43) CA12CA1CA9ALDH1A1MAPT
SCHEMBL7929785 0.81 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL7782792 0.81 ALDH1A1 (0.61) CA12CA1CA2CA7CA9
SCHEMBL6041660 0.81 CA12 (0.49) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10030103-B2 Stable helical ionic polypeptides THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2018-07-24 US disclosed
US-10030103-B2 Stable helical ionic polypeptides THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2018-07-24 US disclosed
EP-2646048-B1 STABLE HELICAL IONIC POLYPEPTIDES UNIV ILLINOIS (US) 2017-11-01 EP disclosed
EP-2847199-B1 PERMEABLE GLYCOSIDASE INHIBITORS AND USES THEREOF MERCK SHARP & DOHME (US) 2017-10-25 EP disclosed
EP-2847199-B1 PERMEABLE GLYCOSIDASE INHIBITORS AND USES THEREOF MERCK SHARP & DOHME (US) 2017-10-25 EP disclosed
US-9793456-B2 Molded resin body for surface-mounted light-emitting device, manufacturing method thereof, and surface-mounted light-emitting device KANEKA CORPORATION (JP) 2017-10-17 US disclosed
US-9611275-B2 Permeable glycosidase inhibitors and uses thereof ALECTOS THERAPEUTICS, INC. (CA) 2017-04-04 US disclosed
US-9611275-B2 Permeable glycosidase inhibitors and uses thereof ALECTOS THERAPEUTICS, INC. (CA) 2017-04-04 US disclosed
US-9611275-B2 Permeable glycosidase inhibitors and uses thereof ALECTOS THERAPEUTICS, INC. (CA) 2017-04-04 US disclosed
US-9496468-B2 Curable resin composition, curable resin composition tablet, molded body, semiconductor package, semiconductor component and light emitting diode KANEKA CORPORATION (JP) 2016-11-15 US disclosed
US-5091274-A Modified polysiloxanes NATIONAL SCIENCE COUNCIL (TW) 1992-02-25 US disclosed
EP-0434840-A1 ORGANIC POLYMER, PREPARATION THEREOF, AND CURABLE COMPOSITION COMPRISING SAME Kanegafuchi Chemical Industry Co., Ltd. (JP) 1991-07-03 EP disclosed
EP-0431173-A1 CURING AGENT, METHOD OF PREPARATION THEREOF, AND CURABLE COMPOSITION PREPARED THEREFROM Kanegafuchi Chemical Industry Co., Ltd. (JP) 1991-06-12 EP disclosed
EP-0415404-A2 Process for producing unsaturated group-terminated high-molecular weight polyalkylene oxide KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-03-06 EP disclosed
EP-0212838-B1 OPTICALLY ACTIVE LIQUID CRYSTAL COMPOUND HAVING METHYLENEOXY GROUP AND COMPOSITION CONTAINING SAME Chisso Corporation (JP) 1990-10-03 EP disclosed
EP-0312967-A1 Sealant for double-layered glass KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-04-26 EP disclosed
US-4729847-A LIGHT SWITCHING ELEMENT CHISSO CORPORATION (JP) 1988-03-08 US disclosed
EP-0212838-A1 Optically active liquid crystal compound having methyleneoxy group and composition containing same Chisso Corporation (JP) 1987-03-04 EP disclosed
US-4398944-A N-ALKOXYPHENYLMETHYL-2-CHLOROACETAMIDE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1983-08-16 US disclosed
US-4221919-A Antiinflammatory substituted phenylacetic acids SPOFA, UNITED PHARMACEUTICAL WORKS (CS) 1980-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10030103-B2 Stable helical ionic polypeptides GHITM, SLC7A1, PICALM CA12 155/4885CA1 163/4885CA2 61/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.