Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23410902 | 0.82 | MAPT (0.41) | ALDH1A1L3MBTL1RXFP1PRNPEGFR | |
| SCHEMBL29892950 | 0.82 | MAPT (0.41) | ALDH1A1L3MBTL1RXFP1PRNPEGFR | |
| SCHEMBL23411784 | 0.81 | KDM4E (0.44) | ALDH1A1EGFRSRCKDM4EHPGD | |
| SCHEMBL23410095 | 0.81 | GSK3B (0.45) | ALDH1A1RXFP1EGFRSRCKDM4E | |
| SCHEMBL25389422 | 0.81 | GSK3B (0.45) | ALDH1A1EGFRKDM4EMAPK1HPGD | |
| SCHEMBL17140259 | 0.78 | MAPT (0.49) | ALDH1A1L3MBTL1RXFP1EGFRKDM4E | |
| SCHEMBL29891647 | 0.78 | MAPT (0.49) | ALDH1A1L3MBTL1RXFP1EGFRKDM4E | |
| SCHEMBL568368 | 0.77 | ALDH1A1 (0.56) | ALDH1A1RXFP1PRNPEGFRSRC | |
| SCHEMBL30099730 | 0.77 | ALDH1A1 (0.56) | ALDH1A1RXFP1PRNPEGFRSRC | |
| SCHEMBL9197584 | 0.77 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1RXFP1KDM4EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018483-A1 | QUINOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-29 | — | — | WO | disclosed |