Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211669 | 0.88 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNACYP1A2ALOX15 | |
| SCHEMBL10625935 | 0.84 | ALDH1A1 (0.37) | ALDH1A1CSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL28145603 | 0.84 | SLC6A4 (0.45) | ALDH1A1MAPTKMT2ALMNACYP3A4 | |
| SCHEMBL27544752 | 0.82 | CSNK2A2 (0.49) | ALDH1A1CSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL9712390 | 0.81 | HPGD (0.42) | ALDH1A1CSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL10407714 | 0.80 | KMT2A (0.52) | ALDH1A1CSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL108670 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MAPTKMT2AUSP2HPGD | |
| SCHEMBL1311470 | 0.79 | ALDH1A1 (0.37) | ALDH1A1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL28278341 | 0.78 | PTGS1 (0.36) | ALDH1A1MAPTCYP3A4PTGS2TSHR | |
| SCHEMBL27299279 | 0.77 | ALDH1A1 (0.32) | ALDH1A1CSNK2A2CSNK2BCSNK2A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |