SCHEMBL27544752

SCHEMBL27544752

Cc1c(Cl)ccc(C(=O)O)c1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.49
CSNK2B P67870 1/20 0.49
CSNK2A1 P68400 1/20 0.49
ALDH1A1 P00352 2/20 0.48
TSHR P16473 2/20 0.48
TP53 P04637 1/20 0.48
CASP1 P29466 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
LMNA P02545 2/20 0.47
CYP1A2 P05177 2/20 0.47
ADRA2A P08913 2/20 0.47
MAPT P10636 2/20 0.47
MEN1 O00255 1/20 0.47
USP2 O75604 1/20 0.47
MT-CO2 P00403 1/20 0.47
TTR P02766 1/20 0.47
PLA2G1B P04054 1/20 0.47
PGR P06401 1/20 0.47
CYP3A4 P08684 1/20 0.47
HTR1A P08908 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31389208 0.85 CYP1A2 (0.58) CSNK2A1ALDH1A1TSHRCASP1SMN1; SMN2
SCHEMBL128319 0.85 CYP1A2 (0.58) CSNK2A1ALDH1A1TSHRCASP1SMN1; SMN2
SCHEMBL108571 0.84 TSHR (0.52) CSNK2A2CSNK2BCSNK2A1ALDH1A1TSHR
SCHEMBL4670497 0.84 TSHR (0.52) CSNK2A2CSNK2BCSNK2A1ALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL29137499 0.83 CYP1A2 (0.55) CSNK2A1ALDH1A1TSHRCASP1SMN1; SMN2
SCHEMBL2255806 0.83 DPP4 (0.52) CSNK2A2CSNK2BCSNK2A1ALDH1A1TSHR
SCHEMBL27280575 0.83 DPP4 (0.52) CSNK2A2CSNK2BCSNK2A1ALDH1A1TSHR
SCHEMBL4143093 0.83 GRM1 (0.51) CSNK2A2CSNK2BCSNK2A1ALDH1A1TSHR
SCHEMBL29042676 0.83 DPP4 (0.47) CSNK2A2CSNK2BCSNK2A1ALDH1A1TSHR
SCHEMBL9712335 0.82 ALDH1A1 (0.38) CSNK2A2CSNK2BCSNK2A1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117425405-A Use of clomazone for improving plant growth and development 沃戴申生命科学美国有限责任公司 2024-01-19 CN disclosed
CN-102066327-A Iminopyridine derivatives and use thereof TAKEDA PHARMACEUTICAL 2011-05-18 CN disclosed
CN-1148385-A 4-benzoylisoxazole derivatives and their use as herbicides RHONE POULENC AGRICULTURE (GB) 1997-04-23 CN disclosed