SCHEMBL9712337

SCHEMBL9712337

Cc1ccc(Cl)c(C(=O)Cl)c1C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
DPP4 P27487 1/20 0.39
KDM4E B2RXH2 1/20 0.38
HSD17B10 Q99714 1/20 0.38
LMNA P02545 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
TAS1R2 Q8TE23 1/20 0.33
MCL1 Q07820 1/20 0.33
TYK2 P29597 1/20 0.33
GAA P10253 3/20 0.33
MAPT P10636 2/20 0.33
AGTR1 P30556 2/20 0.33
MEN1 O00255 1/20 0.33
AKR1B10 O60218 1/20 0.33
ABCB11 O95342 1/20 0.33
TTR P02766 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
CHRM1 P11229 1/20 0.33
FABP2 P12104 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1312577 0.84 ALDH1A1 (0.41) ALDH1A1MCL1MAPTSMN1; SMN2L3MBTL1
SCHEMBL1164172 0.79 ALDH1A1 (0.48) ALDH1A1DPP4KDM4EHSD17B10LMNA
SCHEMBL7744335 0.78 ALDH1A1 (0.46) ALDH1A1DPP4KDM4EHSD17B10LMNA
SCHEMBL302924 0.78 ALDH1A1 (0.37) ALDH1A1LMNAMCL1MEN1AKR1B10
Benzoyl Chloride SCHEMBL8177472 0.77 ALDH1A1 (0.38) ALDH1A1KDM4ELMNAMCL1GAA
SCHEMBL28121436 0.76 ALDH1A1 (0.38) ALDH1A1LMNAMCL1GAAMAPT
SCHEMBL476833 0.74 ALDH1A1 (0.71) ALDH1A1LMNATYK2KMT2AL3MBTL1
SCHEMBL3702506 0.74 TDP1 (0.47) ALDH1A1LMNAMAPTMEN1MAPK1
SCHEMBL1312119 0.72 ALDH1A1 (0.37) ALDH1A1KDM4ELMNAMAPK1SMN1; SMN2
SCHEMBL1313390 0.72 ALDH1A1 (0.61) ALDH1A1DPP4KDM4EHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5117057-A Insecticidal N' substituted-N-N'-disubstituted-hydrazines ROHM AND HAAS COMPANY (US) 1992-05-26 US disclosed