Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | FABP2 | P12104 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090741 | 0.83 | DPP4 (0.48) | ALDH1A1LMNAMAPK1PTGS2MEN1 | |
| SCHEMBL1313390 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPK1MEN1TTRKMT2A | |
| SCHEMBL9712337 | 0.78 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPK1PTGS2MEN1 | |
| SCHEMBL9197919 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPK1TTRKMT2ACYP3A4 | |
| SCHEMBL1164172 | 0.75 | ALDH1A1 (0.48) | ALDH1A1LMNACLCN2DPP4KDM4E | |
| SCHEMBL11674723 | 0.75 | ALDH1A1 (0.41) | ALDH1A1CYP3A4GAACYP1A2MAPT | |
| SCHEMBL1312577 | 0.75 | ALDH1A1 (0.41) | ALDH1A1CYP3A4TSHRCYP1A2MAPT | |
| SCHEMBL476833 | 0.74 | ALDH1A1 (0.71) | ALDH1A1LMNAKMT2ATDP1TYK2 | |
| SCHEMBL7961276 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MAPK1TTRCYP3A4DPP4 | |
| SCHEMBL28145603 | 0.74 | SLC6A4 (0.45) | ALDH1A1LMNAMAPK1KMT2ANR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5113016-A | Manufacture of phthaloyl chlorides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-12 | — | — | US | claimed |
| US-6429334-B1 | CATALYTIC REACTION OF ORGANIC ACID OR ANHYDRIDE AND PHOSGENE IN GROUP IV METAL HALIDE PRESENCE; CHLORINATION, BROMINATION, HALOGENATION, CATALYSIS | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-08-06 | — | — | US | disclosed |
| US-5113016-A | Manufacture of phthaloyl chlorides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-12 | — | — | US | disclosed |