SCHEMBL9712418

SCHEMBL9712418

CCc1ccc(C(=O)c2ccccc2C(=O)Cl)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 1/20 0.49
ALDH1A1 P00352 4/20 0.48
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
AKR1C3 P42330 3/20 0.46
NR4A1 P22736 1/20 0.46
NPC1 O15118 4/20 0.44
RAB9A P51151 3/20 0.44
GAA P10253 2/20 0.43
CDC25B P30305 1/20 0.43
ATM Q13315 1/20 0.43
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
MAPT P10636 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8173743 0.87 ALDH1A1 (0.43) PLK1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL5314074 0.84 AKR1C3 (0.66) PLK1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL14648743 0.84 ALDH1A1 (0.50) PLK1ALDH1A1CYP1A2CYP3A4CYP2C9
Benzene SCHEMBL28564703 0.84 AKR1C3 (0.66) PLK1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL9712617 0.84 PLK1 (0.54) PLK1ALDH1A1CNR2
SCHEMBL28687869 0.83 AKR1C3 (0.64) PLK1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL11613215 0.82 ALDH1A1 (0.52) PLK1ALDH1A1NPSR1L3MBTL1AKR1C3
SCHEMBL9712442 0.82 CNR2 (0.50) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL4354691 0.82 THRA (0.56) PLK1ALDH1A1MAPTKMT2AMEN1
SCHEMBL29157437 0.81 PLK1 (0.47) PLK1ALDH1A1CYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5117057-A Insecticidal N' substituted-N-N'-disubstituted-hydrazines ROHM AND HAAS COMPANY (US) 1992-05-26 US disclosed
US-4312811-A DEHYDROCHLORINATION OF ORTHO-BENZOYLBENZOIC ACID CHLORIDE INTEROX (SOCIETE ANONYME) (BE) 1982-01-26 US disclosed