Tetrahydrofuran

Tetrahydrofuran

SCHEMBL971244

C1CCOC1.CCCC(O)c1cccc2ccccc12

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
KMT2A Q03164 1/20 0.39
GAA P10253 1/20 0.39
CYP1A2 P05177 2/20 0.38
CYP2C19 P33261 2/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP2C9 P11712 1/20 0.38
SLC6A4 P31645 1/20 0.38
AOC3 Q16853 1/20 0.37
CASR P41180 1/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
ACP3 P15309 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2734713 0.88 ALDH1A1 (0.47) TSHRKMT2AGAACYP1A2CYP2C19
Tetrahydrofuran SCHEMBL971565 0.80 CYP1A2 (0.43) GAACYP1A2CYP2C19ALDH1A1CYP2C9
SCHEMBL6313224 0.80 TSHR (0.46) TSHRKMT2AGAACYP1A2CYP2C19
SCHEMBL6055379 0.79 HPRT1 (0.45) TSHRKMT2AGAACYP1A2CYP2C19
SCHEMBL7379765 0.79 PPARG (0.46) TSHRKMT2AGAACYP1A2CYP2C19
SCHEMBL3905545 0.77 PPARG (0.48) TSHRKMT2AGAACYP1A2CYP2C19
SCHEMBL28732572 0.77 PPARG (0.48) TSHRKMT2AGAACYP1A2CYP2C19
SCHEMBL11339313 0.77 PPARG (0.48) TSHRKMT2AGAACYP1A2CYP2C19
SCHEMBL11724981 0.77 PPARG (0.48) TSHRKMT2AGAACYP1A2CYP2C19
SCHEMBL10901230 0.77 PPARG (0.48) TSHRKMT2AGAACYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829897-B1 SUPPORTED NON-METALLOCENE OLEFIN POLYMERIZATION CATALYST, AND PREPARATION AND USE THEREOF YANGZI PETROCHEMICAL COMPANY CO LTD (CN) 2014-12-10 EP disclosed
US-7875568-B2 reacting silica with titanium tetrachloride to obtain a modified carrier, then mixing with a solution of magnesium chloride, filtering, washing, suction and drying, to prepare a composite carriers, used as supports for addition polymerization catalysts, that improve polymer morphology and bulk density YANGZI PETROCHEMICAL COMPANY CO., LTD. (CN) 2011-01-25 US disclosed
US-20080227936-A1 reacting silica with titanium tetrachloride to obtain a modified carrier, then mixing with a solution of magnesium chloride, filtering, washing, suction and drying, to prepare a composite carriers, used as supports for addition polymerization catalysts, that improve polymer morphology and bulk density YANGZI PETROCHEMICAL COMPANY CO., LTD. (CN) 2008-09-18 US disclosed
EP-1829897-A1 SUPPORTED NON-METALLOCENE OLEFIN POLYMERIZATION CATALYST, AND PREPARATION AND USE THEREOF Yangzi Petrochemical Company Co., Ltd. (CN) 2007-09-05 EP disclosed